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Phospho-NMDAR1 (Ser896) Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Synonyms

NMDAR1 C1 (phospho S896) ; p-NMDAR1 C1 (phospho S896) ; NMDAR1 (Phospho-Ser896) ; NMDAR1 (Phospho-S896) ; NMDAR1 C1 (phospho S896) ; p-NMDAR1 (S896) ; p-NMDAR1 (Ser896) ; NMDA-NR1; N-Methyl-d-Asprtate receptor 1; GRIN1; NMDA1; NR1; Glutamate [NMDA] receptor subunit zeta 1; Glutamate receptor ionotropic N methyl D aspartate 1; Grin 1; Grin1; N methyl D aspartate receptor channel; N-methyl-D-aspartate receptor; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; NMDA 1; NMDA NR1; NMDA R1; NMDA receptor 1; NMDA1; NMDAR 1; NMDAR; NR 1; NMDZ1_HUMAN.

Gene ID

2902

Swiss Prot

Q05586

Modification Site

Ser896

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

NMDAR1

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated Synthesised phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser896

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2902

Predicted Cross Reactivity

Rat, Dog, Cow, Chicken

Curated Selection

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