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Phospho-NMDAR1 (Ser896) Polyclonal Antibody, APC Conjugated

Product Specifications

Background

The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

Synonyms

NMDAR1 C1 (phospho S896) ; p-NMDAR1 C1 (phospho S896) ; NMDAR1 (Phospho-Ser896) ; NMDAR1 (Phospho-S896) ; NMDAR1 C1 (phospho S896) ; p-NMDAR1 (S896) ; p-NMDAR1 (Ser896) ; NMDA-NR1; N-Methyl-d-Asprtate receptor 1; GRIN1; NMDA1; NR1; Glutamate [NMDA] receptor subunit zeta 1; Glutamate receptor ionotropic N methyl D aspartate 1; Grin 1; Grin1; N methyl D aspartate receptor channel; N-methyl-D-aspartate receptor; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; NMDA 1; NMDA NR1; NMDA R1; NMDA receptor 1; NMDA1; NMDAR 1; NMDAR; NR 1; NMDZ1_HUMAN.

Gene ID

2902

Swiss Prot

Q05586

Modification Site

Ser896

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Target

NMDAR1

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated Synthesised phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser896

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

2902

Predicted Cross Reactivity

Rat, Dog, Cow, Chicken

Curated Selection

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