Phospho-NMDAR1 (Ser890) Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity) .

Synonyms

NR1; MRD8; GluN1; NMDA1; NMDAR1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; GRIN1

Gene ID

2902

Swiss Prot

Q05586

Modification Site

Ser890

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-NMDAR1 (Ser890)

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser890

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Ser890 in Mouse and Rat.

Gene ID URL

2902

Predicted Cross Reactivity

Mouse, Dog, Cow, Chicken

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