Phospho-NMDAR1 (Ser890) Polyclonal Antibody, AbBy Fluor™ 647 Conjugated
Product Specifications
Background
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity) .
Synonyms
NR1; MRD8; GluN1; NMDA1; NMDAR1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; GRIN1
Gene ID
2902
Swiss Prot
Q05586
Modification Site
Ser890
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Phospho-NMDAR1 (Ser890)
Clonality
Polyclonal
Isotype
IgG
Conjugation
AbBy Fluor™ 647
Source
KLH conjugated synthetic phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser890
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/665nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This phosphorylation site is homologous to that of Ser890 in Mouse and Rat.
Gene ID URL
2902
Predicted Cross Reactivity
Mouse, Dog, Cow, Chicken
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
