Phospho-NMDAR1 (Ser890) Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. This protein plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors (By similarity) .
Synonyms
NR1; MRD8; GluN1; NMDA1; NMDAR1; Glutamate receptor ionotropic, NMDA 1; Glutamate [NMDA] receptor subunit zeta-1; N-methyl-D-aspartate receptor subunit NR1; NMD-R1; GRIN1
Gene ID
2902
Swiss Prot
Q05586
Modification Site
Ser890
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Rat
Target
Phospho-NMDAR1 (Ser890)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic phosphopeptide derived from human NMDAR1 around the phosphorylation site of Ser890
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This phosphorylation site is homologous to that of Ser890 in Mouse and Rat.
Gene ID URL
2902
Predicted Cross Reactivity
Mouse, Dog, Cow, Chicken
Curated Selection
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