Phospho-NDRG1 (Thr346) Polyclonal Antibody
Product Specifications
Background
This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. Mutation in this gene has been reported to be causative for hereditary motor and sensory neuropathy-Lom. May have a growth inhibitory role. Ubiquitous; expressed most prominently in placental membranes and prostate, kidney, small intestine, and ovary tissues. Reduced expression in adenocarcinomas compared to normal tissues. In colon, prostate and placental membranes, the cells that border the lumen show the highest expression.
Synonyms
N-myc downstream regulated gene 1; TDD5; 42 kDa; cap43; cmt4d; Dferentiation related gene1 protein; Drg 1; drg1; gc4; hmsnl; Human mRNA for RTP complete cds; N myc downstream regulated gene 1 protein; Ndr 1; NDRG 1; Nickel specic induction protein Cap43; Nmyc downstream regulated gene1; Protein NDRG1; Protein regulated by oxygen 1 ; Protein regulated by oxygen1; proxy1; reducin; Reducing agents and tunicamycin responsive protein; rit42; rtp; targ1; tdds; tunicamycin-responsive protein.
Gene ID
10397
Modification Site
Thr346
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-NDRG1 (Thr346)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic phosphopeptide derived from human NDRG1 around the phosphorylation site of Thr346
Applications
ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
10397
Predicted Cross Reactivity
Dog, Cow, Horse
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items