Phospho-MEF2A (Thr312) Polyclonal Antibody

Product Specifications

Background

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

Synonyms

Mef2; ADCAD1; RSRFC4; RSRFC9; Myocyte-specific enhancer factor 2A; Serum response factor-like protein 1; MEF2A

Gene ID

4205

Swiss Prot

Q02078

Modification Site

Thr312

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-MEF2A (Thr312)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human MEF2A around the phosphorylation site of Thr312

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

4205

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Horse, Rabbit

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

E28G2202 100 µL

RSK1 p90 (Phospho T573) (14Q4) Rabbit Monoclonal Antibody

Ask

View Details

Amh1132100 500 ng

GFP hsa-mir-4643 AAV miRNA Vector

Ask

View Details

PHY7328S 150 μg

ENODL11 Antibody

Ask

View Details

NBP2-89697UV 0.1 mL

Rabbit Monoclonal CXCL9/MIG Antibody (050) [DyLight 350]

Ask

View Details