Phospho-Mcl1 (Ser159 + Thr163) Polyclonal Antibody, APC-Cy7 Conjugated

Product Specifications

Background

Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.

Synonyms

TM; EAT; MCL1L; MCL1S; Mcl-1; BCL2L3; MCL1-ES; bcl2-L-3; mcl1/EAT; Induced myeloid leukemia cell differentiation protein Mcl-1; Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; MCL1

Gene ID

4170

Swiss Prot

Q07820

Modification Site

Ser159 + Thr163

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Target

Phospho-Mcl1 (Ser159 + Thr163)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy7

Source

KLH conjugated synthetic phosphopeptide derived from human Mcl 1 around the phosphorylation site of Ser159/Thr163

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

These phosphorylation sites are homologous to Ser140 + Thr144 in Mouse and Ser139 + Thr143 in Rat.

Gene ID URL

4170

Predicted Cross Reactivity

Mouse, Dog, Cow, Horse

More Discoveries

Explore Other Products

Browse additional items from our catalog

MBS3233579-01 0.1 mg

Crebzf Peptide - C-terminal region

View Details

MBS3233579-02 5x 0.1 mg

Crebzf Peptide - C-terminal region

View Details

LY413829 100 µg

LIM kinase 2 (LIMK2) (NM_016733) Human Over-expression Lysate

View Details

TU000314 1.0 mL

ADAM33 3'UTR Luciferase Stable Cell Line

View Details

PV063349 500 ng

ARVD4 Protein Vector (Human) (pPB-C-His)

View Details

K1697206 1.0 µg DNA

PPIAP5 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

View Details