Phospho-LKB1 (Ser428) Polyclonal Antibody

Product Specifications

Background

This gene, which encodes a member of the serine/threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in this gene have been associated with Peutz-Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].

Synonyms

STK11phospho S428; LKB 1; LKB1; NY REN 19 antigen; Peutz Jeghers syndrome; PJS; Serine/Threonine Kinase 11; Serine/threonine protein kinase 11; Serine/threonine protein kinase LKB1; STK 11; STK11.

Gene ID

6794

Modification Site

Ser428

Cellular Locus

Cytoplasm, Nucleus, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-LKB1 (Ser428)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic phosphopeptide derived from human LKB1 around the phosphorylation site of Ser428 [RL (p-S) AC]

Applications

WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6794

Predicted Cross Reactivity

Dog, Cow, Horse

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FAB9140W 0.1 mL

Rat Monoclonal IGSF9 Antibody (993107) [DyLight 650]

Ask

View Details

ICH5039-500mg 500 mg

Polatuzumab Biosimilar - Research Grade

Ask

View Details

NBP2-93877-0.1mL 0.1 mL

Rabbit Polyclonal OGDH Antibody

Ask

View Details

MBS1076108-01 0.02 mg (E-Coli)

Recombinant Chloroherpeton thalassium Hydroxyethylthiazole kinase (thiM)

Ask

View Details

MBS1076108-02 0.02 mg (Yeast)

Recombinant Chloroherpeton thalassium Hydroxyethylthiazole kinase (thiM)

Ask

View Details

MBS1076108-03 0.1 mg (E-Coli)

Recombinant Chloroherpeton thalassium Hydroxyethylthiazole kinase (thiM)

Ask

View Details