Exatecan intermediate 10
Exatecan intermediate 10 is an intermediate in the synthesis of Exatecan.Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 of 2[1].2 μM (0[1].975 μg/mL) for use in cancer research[1].
Product Specifications
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
ADC Payload; Topoisomerase
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related; Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/exatecan-intermediate-10.html
Purity
99.92
Solubility
10 mM in DMSO
Smiles
O=C1OCC(C(N2C(C3=NC4=CC(F)=C(C5=C4C([C@@H](CC5)NC(C)=O)=C3C2)C)=C6)=O)=C6[C@@]1(CC)O
Molecular Formula
C26H24FN3O5
Molecular Weight
477.48
Precautions
H302, H315, H319, H335
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Camptothecins
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
45549061 1.0 µg DNA
SSR4 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 
LC405620 20 µg
Gliomedin (GLDN) (NM_181789) Human Over-expression Lysate
Sign In for Pricing
View Details E45H15240-2 20 µg
ZU5 (UNC5CL) (NM_173561) Human Over-expression Lysate
Sign In for Pricing
View Details