DS20362725
DS20362725 is an estrogen-related receptor α (ERRα) agonist. DS20362725 inhibits the binding between receptor-interacting protein 140 (RIP140) corepressor peptide (10 nM) and GST-ERRα ligand-binding domain (LBD; 1.2 μM) with an IC50 value of 0.6 μM. DS20362725 can be used for the research of metabolic disorders, including type 2 diabetes mellitus (T2DM) [1].
Product Specifications
CAS Number
2735803-20-8
UNSPSC
12352005
Target
Estrogen Receptor/ERR
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ds20362725.html
Purity
99.34
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=CC=C(OC2=CC=C3N=C(C)N(C)C3=C2)C=C1C(C)(C)C
Molecular Formula
C19H22N2O2
Molecular Weight
310.39
References & Citations
[1]Shinozuka T, et al. Discovery of a Novel Class of ERRα Agonists. ACS Med Chem Lett. 2021 Apr 21;12 (5) :817-821.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERRα
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD4 Mouse Monoclonal Antibody (SK3), CF®575 Conjugate - Biotium Choice
MC1 Receptor (MC1R) (NM_002386) Human Over-expression Lysate
