Phospho-Histone H3 (Ser28) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
H3t; H3.4; H3/g; H3FT; Histone H3.1t; H3/t; HIST3H3
Gene ID
8290
Swiss Prot
Q16695
Modification Site
Ser28
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Histone H3 (Ser28)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic phosphopeptide derived from human Histone H3 around the phosphorylation site of Ser29
Applications
WB, ELISA, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Specificity
This phosphorylation site is homologous across the listed species.
Gene ID URL
8290
Predicted Cross Reactivity
Mouse, Rat, Cow, Pig, Rabbit, Fruit Fly
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