Phospho-Histone H3 (Ser28) Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms
H3t; H3.4; H3/g; H3FT; Histone H3.1t; H3/t; HIST3H3
Gene ID
8290
Swiss Prot
Q16695
Modification Site
Ser28
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Histone H3 (Ser28)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from human Histone H3 around the phosphorylation site of Ser29
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This phosphorylation site is homologous across the listed species.
Gene ID URL
8290
Predicted Cross Reactivity
Mouse, Rat, Cow, Pig, Rabbit, Fruit Fly
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