What sizes are available for Phospho-H2AX (Ser139) Polyclonal Antibody, APC Conjugated?

Phospho-H2AX (Ser139) Polyclonal Antibody, APC Conjugated is available in the following size(s): 100 µL.

Phospho-H2AX (Ser139) Polyclonal Antibody, APC Conjugated

Q: What is the catalog number for Phospho-H2AX (Ser139) Polyclonal Antibody, APC Conjugated?

The catalog number for Phospho-H2AX (Ser139) Polyclonal Antibody, APC Conjugated is bs-3185R-APC.

Product Specifications

Background

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

Synonyms

H2AX; H2A.X; H2A/X; Histone H2AX; Histone H2A.X; H2AFX

Gene ID

3014

Swiss Prot

P16104

Modification Site

Ser140

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

Phospho-H2AX (Ser139)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic phosphopeptide derived from human Histone H2AX around the phosphorylation site of Ser140

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylation site is homologous to that of Ser140 in Mouse and Rat.

Gene ID URL

3014

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Rabbit

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

bs-1334R-BF680-TR 20 µL

TIE1 Polyclonal Antibody, AbBy Fluor™ 680 Conjugated

Sign In for Pricing

View Details

bs-20595R-PE-01 20 µL

TLR4 Polyclonal Antibody, PE Conjugated

Sign In for Pricing

View Details

bs-20595R-PE-02 100 µL

TLR4 Polyclonal Antibody, PE Conjugated

Sign In for Pricing

View Details

31799015 1.0 µg DNA

Ngf ORF Vector (Mouse) (pORF)

Sign In for Pricing

View Details

TA421608 100 µL

PEPD Rabbit Monoclonal Antibody [Clone ID: R03-7E5]

Sign In for Pricing

View Details

FDA43888-01 50 mg

1,1-Cyclopropanediethanol

Sign In for Pricing

View Details