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DC-05

DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor, with an IC50 and a Kd of 10.3 μM and 1.09 μM, respectively.

Product Specifications

CAS Number

890643-16-0

UNSPSC

12352005

Hazard Statement

H302

Target

DNA Methyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/DC_05.html

Purity

98.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(CNCCC1=CNC2=C1C=CC=C2)CN(C3=CC=CC=C34)C5=C4C=CC=C5

Molecular Formula

C25H25N3O

Molecular Weight

383.49

Precautions

H302

References & Citations

[1]Chen S, et al. Identifying novel selective non-nucleoside DNA methyltransferase 1 inhibitors through docking-based virtual screening. J Med Chem. 2014 Nov 13;57 (21) :9028-41.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

DNMT1

Available Sizes

Frequently Asked Questions

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