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Phospho-Ezrin (Thr567) Polyclonal Antibody, PE-Cy5.5 Conjugated

Product Specifications

Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Synonyms

Ezrin phospho T567; Ezrin phospho Thr567; p-Ezrin phospho T567; CVIL; CVL; cytovillin 2 ; Cytovillin ; DKFZp762H157; FLJ26216; MGC1584; p81; VIL 2 ; VIL2; Villin 2; Villin2; EZRI_HUMAN.

Gene ID

7430

Modification Site

Thr567

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-Ezrin (Thr567)

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy5.5

Source

KLH conjugated synthetic phosphopeptide derived from human Ezrin around the phosphorylation site of Thr567

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

7430

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit, Guinea Pig

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