Phospho-BMX (Tyr40) Polyclonal Antibody, APC-Cy5.5 Conjugated
Product Specifications
Background
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
Synonyms
BMX phospho Y40; BMX phospho Try40; BMX p-Y40; BMX p-Try40; p-BMX phospho Y40; BMX/ETK Tyr40; p-ETK Tyr40; Protein tyrosine kinase BMX; PSCTK 2; PSCTK 3; PSCTK2; PSCTK3; Bone marrow tyrosine kinase gene in chromosome X protein; BMX non receptor tyrosine kinase; Cytoplasmic tyrosine protein kinase BMX; Epithelial and endothelial tyrosine kinase; BMX_HUMAN; Cytoplasmic tyrosine-protein kinase BMX; ETK; NTK38; Protein tyrosine kinase BMX; Etk; Etk/Bmx; Tyro8.
Gene ID
660
Modification Site
Tyr40
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Rat
Target
Phospho-BMX (Tyr40)
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy5.5
Source
KLH conjugated synthetic phosphopeptide derived from human ETK around the phosphorylation site of Tyr40
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/694nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
660
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
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