Phospho-DOK2 (Tyr142) Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]

Synonyms

DOK2 Tyr139; p-DOK2 Tyr139; Docking protein 2 56kDa; Docking protein 2 antibody DOK 2; DOK R; Downstream of tyrosine kinase 2; p56dok 2; p56dok 2; p56DOK; p56dok2

Gene ID

9046

Modification Site

Tyr139

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Mouse

Target

Phospho-DOK2 (Tyr142)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic phosphopeptide derived from human p56Dok2 around the phosphorylation site of Tyr139

Applications

WB, ELISA, IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

9046

Predicted Cross Reactivity

Human, Rat, Dog, Cow, Pig, Horse, Chicken

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