Phospho-cdc25A (Thr507) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Synonyms
CDC25A2; M-phase inducer phosphatase 1; Dual specificity phosphatase Cdc25A; CDC25A
Gene ID
993
Swiss Prot
P30304
Modification Site
Thr507
Cellular Locus
Cytoplasm, Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse
Target
Phospho-cdc25A (Thr507)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic phosphopeptide derived from human cdc25A around the phosphorylation site of Thr507 [SR (p-T) WA]
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Specificity
This phosphorylation site is homologous to Thr497 in Mouse and Thr508 in Rat.
Gene ID URL
993
Predicted Cross Reactivity
Rat, Dog, Cow, Chicken
Curated Selection
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