Phospho-Bcl-2 (Ser70) Polyclonal Antibody, PE-Cy7 Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Bcl-2; Apoptosis regulator Bcl-2; Bcl2
Gene ID
24224
Swiss Prot
P49950
Modification Site
Ser70
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Bcl-2 (Ser70)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy7
Source
KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70
Applications
WB, FCM
Purification
Purified by Protein A.
Excitation Emission
488nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
24224
Predicted Cross Reactivity
Mouse, Rat, Dog, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1170770-01 0.02 mg (E-Coli)
Recombinant Escherichia coli O17:K52:H18 Ribosome-binding factor A (rbfA)
Ask
View Details MBS1170770-02 0.1 mg (E-Coli)
Recombinant Escherichia coli O17:K52:H18 Ribosome-binding factor A (rbfA)
Ask
View Details 
MBS1170770-03 0.02 mg (Yeast)
Recombinant Escherichia coli O17:K52:H18 Ribosome-binding factor A (rbfA)
Ask
View Details MBS1170770-04 0.1 mg (Yeast)
Recombinant Escherichia coli O17:K52:H18 Ribosome-binding factor A (rbfA)
Ask
View Details