Phospho-Bcl-2 (Ser70) Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1) .
Synonyms
Bcl-2; Apoptosis regulator Bcl-2; Bcl2
Gene ID
24224
Swiss Prot
P49950
Modification Site
Ser70
Cellular Locus
Cytoplasm, Nucleus, Cell membrane
Host
Rabbit
Cross Reactivity
Human
Target
Phospho-Bcl-2 (Ser70)
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic phosphopeptide derived from rat Bcl-2 around the phosphorylation site of Ser70
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
24224
Predicted Cross Reactivity
Mouse, Rat, Dog, Rabbit
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
QP5871-ec-100ug 100ug
Recombinant Human Gamma-crystallin D Protein, GST, E.coli-100ug
Ask
View Details 
GTR15380812 1 Vial
Lentiviral human EHD1 sgRNA gene knockout kit - Lentiviral human EHD1 sgRNA gene knockout kit (100)
Ask
View Details SR300962 1 Kit
Carboxypeptidase N subunit 2 (CPN2) Human siRNA Oligo Duplex (Locus ID 1370)
Ask
View Details