Phospho-Aurora B (Thr232) + Aurora C (Thr198) Polyclonal Antibody, PerCP-Cy5.5 Conjugated

Product Specifications

Background

Aurora B is a mitotic protein kinase that phosphorylates histone H3 (probably on Serine 10), behaves as a chromosomal passenger protein, and may regulate several stages of mitosis such as centrosome separation, chromosome segregation and cytokinesis. It localizes to the inner centromere region from prophase to anaphase.

Synonyms

Aurora B phospho T232; p-Aurora B phospho T232; AIK2; AIM1; ARK2; AurB; AURKB; Aurora 1; Aurora and Ipl1 like midbody associated protein 1; Aurora kinase B; Aurora related kinase 2; Aurora-B; Aurora/IPL1 related kinase 2; IPL1; Serine/theronine kinase 12; Serine/threonine protein kinase 12; STK1; STK12; STK5; AURKB_HUMAN.

Gene ID

9212

Modification Site

Thr198

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Cross Reactivity

Human

Target

Phospho-Aurora B (Thr232) + Aurora C (Thr198)

Clonality

Polyclonal

Isotype

IgG

Conjugation

PerCP-Cy5.5

Source

KLH conjugated synthetic phosphopeptide derived from human Aurora B around the phosphorylation site of Thr232

Applications

Purification

Purified by Protein A.

Excitation Emission

482nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9212

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Sheep, Pig, Horse, Rabbit

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