Phospho-p53BP1 (Ser25 + Ser29) Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Plays a key role in the response to DNA damage. May have a role in checkpoint signaling during mitosis. Enhances TP53-mediated transcriptional activation.

Synonyms

P202; 53BP1; Tumor suppressor p53-binding protein 1; p53-binding protein 1; p53BP1; TP53BP1

Gene ID

7158

Swiss Prot

Q12888

Modification Site

Ser25 + Ser29

Cellular Locus

Nucleus

Host

Rabbit

Cross Reactivity

Mouse, Rat

Target

Phospho-p53BP1 (Ser25 + Ser29)

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic phosphopeptide derived from human p53BP1 around the phosphorylation site of Ser25/29

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This phosphorylated site is the same in Mouse and homologous to p53BP1 Ser30 + Ser34 in Rat.

Gene ID URL

7158

Predicted Cross Reactivity

Human, Dog, Cow, Pig, Horse, Rabbit

Curated Selection

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