Phospho-Bax (Ser184) Polyclonal Antibody, PE-Cy5 Conjugated
Product Specifications
Background
Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Synonyms
BCL2L4; Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4; BAX
Gene ID
581
Swiss Prot
Q07812
Modification Site
Ser184
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Target
Phospho-Bax (Ser184)
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE-Cy5
Source
KLH conjugated synthetic phosphopeptide derived from human Bax around the phosphorylation site of Ser184
Applications
WB, Flow-Cyt
Purification
Purified by Protein A.
Excitation Emission
488nm/670nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), Flow-Cyt (1ug/Test)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Phosphorylation
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
581
Predicted Cross Reactivity
Dog, Cow, Sheep, Pig
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC470902-500 1x 500 µL
Nucleolin (NCL/902), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC682746-100 1x 100 µL
PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) (PDL1/2746), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940183-100 1x 100 µL
Cytochrome C (Mitochondrial Marker) (7H8.2C12), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940700-500 1x 500 µL
MART-1 / Melan-A (M2-7C10 + M2-9E3 + A103), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details