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Phospho-AR/Androgen receptor (Ser597) Polyclonal Antibody, Biotin Conjugated

Product Specifications

Background

Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3.

Synonyms

Androgen receptor; Dihydrotestosterone receptor; Nuclear receptor subfamily 3 group C member 4; AR; DHTR; NR3C4

Gene ID

367

Modification Site

Ser597

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat, Bovine

Target

Phospho-AR/Androgen receptor (Ser597)

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Source

KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser597 [CA (p-S) RN]

Applications

IHC-P, IHC-F

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

IHC-P (1:200-400), IHC-F (1:100-500)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Phosphorylation

Storage Conditions

Store at -20°C for 12 months.

Gene ID URL

367

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