HES1 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity) . May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.
Synonyms
HHL; HRY; HES-1; bHLHb39; Transcription factor HES-1; Class B basic helix-loop-helix protein 39; Hairy and enhancer of split 1; Hairy homolog; Hairy-like protein; HES1; HL
Gene ID
3280
Swiss Prot
Q14469
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
41-150/280
Target
HES1
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human HES1
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
3280
Predicted Cross Reactivity
Cow, Pig, Horse, Rabbit
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY402571 100 µg
Myozenin 2 (MYOZ2) (NM_016599) Human Over-expression Lysate
Sign In for Pricing
View Details 
![C19orf80 (ANGPTL8) Mouse Monoclonal Antibody [Clone ID: OTI5E2]](https://cdn.genprice.uk/products/937/68dd18ba061270361e9083d2/imageurl/cf808735.webp)
CF808735 100 µg
C19orf80 (ANGPTL8) Mouse Monoclonal Antibody [Clone ID: OTI5E2]
Sign In for Pricing
View Details