TNFR1 Polyclonal Antibody, PerCP Conjugated
Product Specifications
Background
Receptor for TNFSF2/TNF-alpha and homotrimeric TNFSF1/lymphotoxin-alpha. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Contributes to the induction of non-cytocidal TNF effects including anti-viral state and activation of the acid sphingomyelinase.
Synonyms
Tumor necrosis factor receptor superfamily member 1A; Tumor necrosis factor receptor 1; TNF-R1; Tumor necrosis factor receptor type I; TNF-RI; TNFR-I; p55; p60; CD120a; TNFRSF1A; TNFAR; TNFR1
Gene ID
7132
Swiss Prot
P19438
Cellular Locus
Secreted, Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse, Rat
Immunogen
1-100/455
Target
TNFR1
Clonality
Polyclonal
Isotype
IgG
Conjugation
PerCP
Source
KLH conjugated synthetic peptide derived from human TNF Receptor I
Applications
WB, FCM, IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
482nm/677nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Specificity
This antibody will recognize Isoform 1, 4 and 5, but not Isoform 2 or 3.
Gene ID URL
7132
Predicted Cross Reactivity
Dog, Cow, Pig, Horse, Rabbit
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
V0285 00100 100 mL
Stoke’s Reagent (As Reducing Agent-Blood Examination)
Sign In for Pricing
View Details 
K6167405 3x 1.0 µg
Foxn4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details 
orb3007007-01 20 µg
Recombinant Human Putative butyrophilin-like protein 10 pseudogene (BTNL10P), partial
Sign In for Pricing
View Details orb3007007-02 100 µg
Recombinant Human Putative butyrophilin-like protein 10 pseudogene (BTNL10P), partial
Sign In for Pricing
View Details orb3007007-03 1 mg
Recombinant Human Putative butyrophilin-like protein 10 pseudogene (BTNL10P), partial
Sign In for Pricing
View Details