ARHG7 Polyclonal Antibody, Cy5.5 Conjugated

ARHGEF7 is a p21-activated protein kinase (Pak) -interacting exchange factor that has been identified as a putative guanine nucleotide exchange factor (GEF) for Rac/Cdc42. It is expressed ubiquitously in all the tissue examined and other isoforms are expressed mainly in the central nervous system. Regulated phosphorylation of ARHGEF7 is necessary to maintain the balance between normal signalling by EGFR and Src versus aberrant growth and transformation.Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene, but some of their full-length sequences have not been determined.

ARHG7_HUMAN; ARHG7; ARHGEF 7; ARHGEF7; Beta pix; betaPix; betaPix-b; betaPix-c; Cool; COOL1; P50 antibody P50BP; P85; P85COOL1; P85SPR; PAK interacting exchange factor beta; PAK3; Pak3bp; PAK3BP; PIX; PIXB; Rho guanine nucleotide exchange factor GEF 7; Rho guanine nucleotide exchange factor GEF 7b; Rho guanine nucleotide exchange factor GEF7; Rho guanine nucleotide exchange factor 7; SH3 domain containing proline rich protein; Nbla10314; KIAA0142.