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SRPK1 Polyclonal Antibody

Product Specifications

Background

Plays a central role in the regulatory network for splicing, controlling the intranuclear distribution of splicing factors in interphase cells and the reorganization of nuclear speckles during mitosis. Hyperphosphorylates RS domain-containing proteins such as SFRS1, SFRS2 and ZRSR2 on serine residues during metaphase but at lower levels during interphase. Locks onto SFRS1 to form a stable complex and processively phosphorylates the RS domain. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral capsids.

Synonyms

Serine/arginine rich protein specic kinase 1; Serine/arginine-rich protein-specic kinase 1; Serine/threonine protein kinase SRPK1; Serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR protein kinase 1; SR protein specic kinase 1; SR-protein-specic kinase 1; SRPK1; SRPK1_HUMAN.

Gene ID

6732

Cellular Locus

Cytoplasm, Nucleus

Host

Rabbit

Immunogen

551-655/655

Target

SRPK1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Unconjugated

Source

KLH conjugated synthetic peptide derived from human SRPK1

Applications

ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Concentration

1µg/µl

Dilution

ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Gene ID URL

6732

Predicted Cross Reactivity

Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit

Available Sizes

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