LRP6 Polyclonal Antibody
Product Specifications
Background
This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009].
Synonyms
ADCAD2; C030016K15Rik; Cd; FLJ90062; FLJ90421; Low density lipoprotein receptor related protein 6; LRP6_HUMAN; Low-density lipoprotein receptor-related protein 6; low-density lipoprotein receptor-related protein 6 precursor; LRP-6; LRP-5; LR3; LRP7; Low-density lipoprotein receptor-related protein 5.
Gene ID
4040, 4041
Cellular Locus
Cytoplasm, Cell membrane
Host
Rabbit
Immunogen
451-550/1613
Target
LRP6
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human LRP6
Applications
ELISA, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
ELISA (1:500-1000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Product Datasheet
https://www.biossantibodies.com/datasheets/bs-2905R
Gene ID URL
4040, 4041
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1252272-01 0.02 mg (E-Coli)
Recombinant Salmonella heidelberg DNA mismatch repair protein mutH (mutH)
Ask
View Details MBS1252272-02 0.1 mg (E-Coli)
Recombinant Salmonella heidelberg DNA mismatch repair protein mutH (mutH)
Ask
View Details MBS1252272-03 0.02 mg (Yeast)
Recombinant Salmonella heidelberg DNA mismatch repair protein mutH (mutH)
Ask
View Details 
MBS1252272-04 0.1 mg (Yeast)
Recombinant Salmonella heidelberg DNA mismatch repair protein mutH (mutH)
Ask
View Details MBS1252272-05 0.02 mg (Baculovirus)
Recombinant Salmonella heidelberg DNA mismatch repair protein mutH (mutH)
Ask
View Details MBS1252272-06 0.02 mg (Mammalian-Cell)
Recombinant Salmonella heidelberg DNA mismatch repair protein mutH (mutH)
Ask
View Details