Gab2 Polyclonal Antibody, APC Conjugated

Product Specifications

Background

Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis.

Synonyms

GRB2-associated-binding protein 2; GRB2-associated binder 2; Growth factor receptor bound protein 2-associated protein 2; pp1; GAB2; KIAA571

Gene ID

9846

Swiss Prot

Q9UQC2

Cellular Locus

Cytoplasm, Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Immunogen

601-676/676

Target

Gab2

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC

Source

KLH conjugated synthetic peptide derived from human Gab2

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

650nm/660nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

9846

Predicted Cross Reactivity

Dog, Cow, Pig, Horse, Rabbit

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

FAB970Y 0.1 mL

Mouse Monoclonal TIMP-1 Antibody (63515) [DyLight 680]

Ask

View Details

SP035 10 mg

Chicken IgG

Ask

View Details

ABP52747-01 30 µL

α-protein Kinase 1 Polyclonal Antibody

Ask

View Details

ABP52747-02 100 µL

α-protein Kinase 1 Polyclonal Antibody

Ask

View Details

ABP52747-03 200 µL

α-protein Kinase 1 Polyclonal Antibody

Ask

View Details

TRC-D456402-5MG 5 mg

2,3:4,5-Di-O-isopropylidene-Beta-D-fructopyranose-d12

Ask

View Details