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LPA2 Polyclonal Antibody, FITC Conjugated

Product Specifications

Background

EDG4 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. There are eight known members of the EDG receptor family and they are implicated in mediating growth-related effects such as induction of cellular proliferation, alterations in differentiation and survival, and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG4 is expressed in testes, ovarian tumor, and leukocyte containing tissues.

Synonyms

Endothelial Cell Dferentiation Gene 4; Endothelial dferentiation lysophosphatidic acid G protein coupled receptor 4; IPA2; LPA receptor 2; LPA receptor EDG4; LPA2; LPAR2; Lysophosphatidic acid receptor Edg4; Edg4; LPAR2_HUMAN.

Gene ID

9170

Cellular Locus

Cytoplasm

Host

Rabbit

Cross Reactivity

Human, Mouse, Rat

Target

LPA2

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Source

KLH conjugated synthetic peptide derived from human EDG4

Applications

IF, Flow-Cyt

Purification

Purified by Protein A.

Excitation Emission

494nm/518nm

Concentration

1µg/µl

Dilution

IF (), Flow-Cyt (1ug/Test)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-2881R-FITC

Gene ID URL

9170

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