CACNA1C Polyclonal Antibody, Cy7 Conjugated
Product Specifications
Background
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]
Synonyms
VDCC-L alpha 1; L-VDCC alpha 1; Voltage dependent calcium channel subunit alpha 1; CACNL1A1; Alpha1c L-type VDCC; CACBR; CACH2; CACN2; CACNA1C; CACNL1A1; CaV1.2; CCHL1A1; L-TYPE CALCIUM CHANNEL ALPHA1C; L-type voltage dependent calcium channel a1; L-TYPE VOLTAGE DEPENDENT CALCIUM CHANNEL ALPHA 1.2; L-VDCC ALPHA1; LOC283439; MGC120730; RATIVS302; TS; CAC1C_HUMAN.
Gene ID
775
Cellular Locus
Cell membrane
Host
Rabbit
Immunogen
1001-1100/2221
Target
CACNA1C
Clonality
Polyclonal
Isotype
IgG
Conjugation
Cy7
Source
KLH conjugated synthetic peptide derived from human VDCC-L alpha
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
743nm/767nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
775
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Rabbit
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
