SMO Polyclonal Antibody
Product Specifications
Background
G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO) . Required for the accumulation of KIF7 and GLI3 in the cilia.
Synonyms
Gx; SMOH; FZD11; Smoothened homolog; SMO; Protein Gx
Gene ID
6608
Swiss Prot
Q99835
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
551-650/787
Target
SMO
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human Smoothened
Applications
WB, ELISA, IHC-P, IF (IHC-P)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IF (IHC-P) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
6608
Predicted Cross Reactivity
Rat, Dog, Cow, Sheep, Horse, Rabbit
Available Sizes
Curated Selection
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