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CRHR2 Polyclonal Antibody, Cy5 Conjugated

Product Specifications

Background

G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

Synonyms

CRF2; CRFR2; CRF-RB; HM-CRF; Corticotropin-releasing factor receptor 2; CRF-R-2; CRF-R2; CRFR-2; Corticotropin-releasing hormone receptor 2; CRH-R-2; CRH-R2; CRHR2; CRF2R; CRH2R

Gene ID

1395

Swiss Prot

Q13324

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Mouse

Immunogen

51-150/411

Target

CRHR2

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy5

Source

KLH conjugated synthetic peptide derived from human CRHR2

Applications

WB, IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

625,650nm/670nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Specificity

This antibody may cross react with CRHR1.

Gene ID URL

1395

Predicted Cross Reactivity

Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit

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