Claudin 4 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.
Synonyms
CPER; CPE-R; CPETR; CPETR1; WBSCR8; hCPE-R; Claudin-4; Clostridium perfringens enterotoxin receptor; CPE-receptor; Williams-Beuren syndrome chromosomal region 8 protein; CLDN4
Gene ID
1364
Swiss Prot
O14493
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
21-120/209
Target
Claudin 4
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human CLDN4
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
1364
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Sheep, Pig, Horse, Chicken, Rabbit
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