DARPP32 Polyclonal Antibody
Product Specifications
Background
This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Synonyms
DARPP32; DARPP-32; Protein phosphatase 1 regulatory subunit 1B; Dopamine- and cAMP-regulated neuronal phosphoprotein; PPP1R1B
Gene ID
84152
Swiss Prot
Q9UD71
Cellular Locus
Cytoplasm
Host
Rabbit
Cross Reactivity
Rat, GuineaPig
Immunogen
51-150/204
Target
DARPP32
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
KLH conjugated synthetic peptide derived from human DARPP32
Applications
WB, ELISA, IHC-P, IHC-F, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Gene ID URL
84152
Predicted Cross Reactivity
Human, Mouse, Dog, Cow, Pig, Horse, Rabbit
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