MCM5 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity (By similarity) . Interacts with MCMBP.
Synonyms
CDC46; P1-CDC46; DNA replication licensing factor MCM5; CDC46 homolog; MCM5
Gene ID
4174
Swiss Prot
P33992
Cellular Locus
Nucleus
Host
Rabbit
Cross Reactivity
Human
Immunogen
651-734/734
Target
MCM5
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human MCM5
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
4174
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow, Horse, Rabbit
Curated Selection
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