CD108 Polyclonal Antibody, FITC Conjugated
Product Specifications
Background
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Synonyms
JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1; Semaphorin-7A; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; SEMA7A
Gene ID
8482
Swiss Prot
O75326
Cellular Locus
Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human
Immunogen
351-450/666
Target
CD108
Clonality
Polyclonal
Isotype
IgG
Conjugation
FITC
Source
KLH conjugated synthetic peptide derived from human Semaphorin 7A
Applications
WB, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
494nm/518nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
8482
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K6029904 1.0 µg DNA
RGD1559896 sgRNA CRISPR Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details 
039737-ML550 100 µL
PCDHA8, CT (PCDHA8, Protocadherin alpha-8) (MaxLight 550) discontinued
Sign In for Pricing
View Details MBS6337464-01 0.1 mL
PRL, Phosphorylated (S207) (PRL, Prolactin) (MaxLight 550)
Sign In for Pricing
View Details