CD108 Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Plays an important role in integrin-mediated signaling and functions both in regulating cell migration and immune responses. Promotes formation of focal adhesion complexes, activation of the protein kinase PTK2/FAK1 and subsequent phosphorylation of MAPK1 and MAPK3. Promotes production of proinflammatory cytokines by monocytes and macrophages. Plays an important role in modulating inflammation and T-cell-mediated immune responses. Promotes axon growth in the embryonic olfactory bulb. Promotes attachment, spreading and dendrite outgrowth in melanocytes.
Synonyms
JMH; CD108; SEMAL; CDw108; SEMAK1; H-Sema-L; H-SEMA-K1; Semaphorin-7A; JMH blood group antigen; John-Milton-Hargen human blood group Ag; Semaphorin-K1; Sema K1; Semaphorin-L; Sema L; SEMA7A
Gene ID
8482
Swiss Prot
O75326
Cellular Locus
Cell membrane, Extracellular matrix
Host
Rabbit
Cross Reactivity
Human
Immunogen
351-450/666
Target
CD108
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Semaphorin 7A
Applications
WB, ELISA, IHC-P, IHC-F
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400), IHC-F (1:100-500)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
8482
Predicted Cross Reactivity
Mouse, Rat, Dog, Cow
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7203935-01 48 Well
Bovine Coiled-coil and C2 domain-containing protein 1B (CC2D1B) ELISA Kit
Ask
View Details MBS7203935-02 96 Well
Bovine Coiled-coil and C2 domain-containing protein 1B (CC2D1B) ELISA Kit
Ask
View Details