Plexin A1 Polyclonal Antibody, PE Conjugated
Product Specifications
Background
Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity) .
Synonyms
NOV; NOVP; PLXN1; PLEXIN-A1; Semaphorin receptor NOV; PLXNA1
Gene ID
5361
Swiss Prot
Q9UIW2
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Rat
Immunogen
901-1000/1896
Target
Plexin A1
Clonality
Polyclonal
Isotype
IgG
Conjugation
PE
Source
KLH conjugated synthetic peptide derived from human Plexin A1
Applications
IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
496,564nm/578nm
Concentration
1µg/µl
Dilution
IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5361
Predicted Cross Reactivity
Human, Mouse, Dog, Pig, Horse, Rabbit, GuineaPig
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