Plexin A1 Polyclonal Antibody, Cy3 Conjugated

Product Specifications

Background

Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm (By similarity) .

Synonyms

NOV; NOVP; PLXN1; PLEXIN-A1; Semaphorin receptor NOV; PLXNA1

Gene ID

5361

Swiss Prot

Q9UIW2

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Rat

Immunogen

901-1000/1896

Target

Plexin A1

Clonality

Polyclonal

Isotype

IgG

Conjugation

Cy3

Source

KLH conjugated synthetic peptide derived from human Plexin A1

Applications

IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

512,550nm/570,615nm

Concentration

1µg/µl

Dilution

IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5361

Predicted Cross Reactivity

Human, Mouse, Dog, Pig, Horse, Rabbit, GuineaPig

Curated Selection

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