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GPNMB Polyclonal Antibody, RBITC Conjugated

Product Specifications

Background

The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Synonyms

NMB; HGFIN; Transmembrane glycoprotein NMB; Transmembrane glycoprotein HGFIN; GPNMB; UNQ1725/PRO9925

Gene ID

10457

Swiss Prot

Q14956

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

81-180/572

Target

GPNMB

Clonality

Polyclonal

Isotype

IgG

Conjugation

RBITC

Source

KLH conjugated synthetic peptide derived from human GPNMB

Applications

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

570nm/595nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.biossantibodies.com/datasheets/bs-2684R-RBITC

Gene ID URL

10457

Predicted Cross Reactivity

Mouse, Cow, Pig, Horse, GuineaPig

Available Sizes

Curated Selection

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