CD112 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated

Product Specifications

Background

Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.

Synonyms

HVEB; PRR2; CD112; PVRR2; Nectin-2; Herpes virus entry mediator B; Herpesvirus entry mediator B; Poliovirus receptor-related protein 2; PVRL2

Gene ID

5819

Swiss Prot

Q92692

Cellular Locus

Cell membrane

Host

Rabbit

Cross Reactivity

Human

Immunogen

251-350/538

Target

CD112

Clonality

Polyclonal

Isotype

IgG

Conjugation

AbBy Fluor™ 488

Source

KLH conjugated synthetic peptide derived from human nectin 2

Applications

WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)

Purification

Purified by Protein A.

Excitation Emission

499nm/519nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

5819

Predicted Cross Reactivity

Mouse, Rat, Cow, Horse

Available Sizes

Curated Selection

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