CD112 Polyclonal Antibody, APC-Cy7 Conjugated
Product Specifications
Background
Nectin 2 is a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. Can form trans-heterodimers with PVRL3/nectin-3.
Synonyms
HVEB; PRR2; CD112; PVRR2; Nectin-2; Herpes virus entry mediator B; Herpesvirus entry mediator B; Poliovirus receptor-related protein 2; PVRL2
Gene ID
5819
Swiss Prot
Q92692
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human
Immunogen
251-350/538
Target
CD112
Clonality
Polyclonal
Isotype
IgG
Conjugation
APC-Cy7
Source
KLH conjugated synthetic peptide derived from human nectin 2
Applications
WB, FCM, IF (IHC-P), IF (IHC-F), IF (ICC)
Purification
Purified by Protein A.
Excitation Emission
650nm/780nm
Concentration
1µg/µl
Dilution
WB (1:300-5000), FCM (1:20-100), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Gene ID URL
5819
Predicted Cross Reactivity
Mouse, Rat, Cow, Horse
Curated Selection
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