IL22R Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.
Synonyms
IL22R; CRF2-9; IL22R1; Interleukin-22 receptor subunit alpha-1; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; ZcytoR11; IL22RA1
Gene ID
58985
Swiss Prot
Q8N6P7
Cellular Locus
Cell membrane
Host
Rabbit
Cross Reactivity
Human, Mouse
Immunogen
41-150/574
Target
IL22R
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human IL-22R
Applications
WB, ELISA, IHC-P
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000), IHC-P (1:200-400)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
58985
Predicted Cross Reactivity
Rat, Dog, Cow, Pig, Horse, Rabbit, GuineaPig
Curated Selection
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