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IL21 Polyclonal Antibody, APC-Cy5.5 Conjugated

Product Specifications

Background

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG (1) and IgG (3) in B-cells (By similarity) . May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.

Synonyms

Za11; IL-21; CVID11; Interleukin-21; IL21

Gene ID

59067

Swiss Prot

Q9HBE4

Cellular Locus

Secreted

Host

Rabbit

Cross Reactivity

Human

Immunogen

65-155/155

Target

IL21

Clonality

Polyclonal

Isotype

IgG

Conjugation

APC-Cy5.5

Source

KLH conjugated synthetic peptide derived from human IL-21

Applications

WB, IF (IHC-P)

Purification

Purified by Protein A.

Excitation Emission

650nm/694nm

Concentration

1µg/µl

Dilution

WB (1:300-5000), IF (IHC-P) (1:50-200)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

59067

Predicted Cross Reactivity

Mouse, Rat, Dog, Cow, Pig

Curated Selection

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