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IL15RA Polyclonal Antibody, PE-Cy7 Conjugated

Product Specifications

Background

IL15RA is a cytokine receptor that specifically binds IL15 with high affinity. It shares two subunits with the receptor of IL2, the IL2R beta and IL2R gamma chains. This forms the basis of many overlapping biological activities of IL15 and IL2. The IL2 receptor requires an additional IL2-specific alpha subunit for high affinity IL2 binding. This protein is structurally related to IL2R alpha, but is capable of binding IL15 with high affinity independent of other subunits, which suggests the distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. There are nine different isoforms.

Synonyms

Interleukin-15 receptor subunit alpha; IL 15R alpha; IL15RA; Interleukin 15 receptor alpha; Interleukin 15 receptor subunit alpha; Soluble interleukin 15 receptor subunit alpha; I15RA_HUMAN.

Gene ID

3601

Cellular Locus

Cytoplasm, Nucleus, Secreted, Cell membrane, Extracellular matrix

Host

Rabbit

Cross Reactivity

Human, Rat

Immunogen

51-150/267

Target

IL15RA

Clonality

Polyclonal

Isotype

IgG

Conjugation

PE-Cy7

Source

KLH conjugated synthetic peptide derived from human IL-15RA

Applications

WB

Purification

Purified by Protein A.

Excitation Emission

488nm/780nm

Concentration

1µg/µl

Dilution

WB (1:300-5000)

Buffer

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Modification

Unmodified

Storage Conditions

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Gene ID URL

3601

Predicted Cross Reactivity

Mouse, Dog, Cow, Horse, Rabbit

Curated Selection

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