Furaprofen

Furaprofen (R803) is an effective HCV replication inhibitor. Furaprofen (R803) is substantially more potent against genotype 1a and 1b replicons (EC50, ~30 nM) than against the genotype 2a replicon (EC50, ~1,000 nM) .

Product Specifications

CAS Number

[67700-30-5]

Product Name Alternative

R803

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

HCV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/R803.html

Purity

99.78

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

OC(C(C1=CC=CC2=C1OC=C2C3=CC=CC=C3)C)=O

Molecular Formula

C17H14O3

Molecular Weight

266.29

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Huang P, et al. Discovery and characterization of substituted diphenyl heterocyclic compounds as potent and selective inhibitors of hepatitis C virus replication. Antimicrob Agents Chemother. 2008 Apr;52 (4) :1419-29.