Granzyme B + D + E + N + G + F + H Polyclonal Antibody, Biotin Conjugated
Product Specifications
Background
Protease required for lymphocyte cytotoxic granules to lyse target cells [RGD]. Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.
Synonyms
Granzyme D; Granzyme B; Granzyme E; Granzyme N; Granzyme G; Granzyme F; Granzyme H; Cathepsin G-like 2; CCP-X; CCP3; CCP4; CCP5; CGL-2; CSP-C; Ctla-5; Ctla-6; , Ctla-7; CTLA1; CTSGL2; Grz d; Grz e; Grz f; Grz g; GZMD; Gzme; Gzmf; Gzmg; GZMH; MCSP-2; MCSP-3; MGC117682; Rnkp7; mast cell proteinase-3-like; Cytotoxic T-lymphocyte proteinase; Granzyme H precursor; Cytotoxic serine protease-C; CSP-C.
Gene ID
2999
Cellular Locus
Cytoplasm, Nucleus, Secreted, Cell membrane
Host
Rabbit
Immunogen
151-252/252
Target
Granzyme B + D + E + N + G + F + H
Clonality
Polyclonal
Isotype
IgG
Conjugation
Biotin
Source
KLH conjugated synthetic peptide derived from human Granzyme D/B/E/N/G/F/H
Applications
WB, ELISA
Purification
Purified by Protein A.
Concentration
1µg/µl
Dilution
WB (1:300-5000), ELISA (1:500-1000)
Buffer
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Modification
Unmodified
Storage Conditions
Store at -20°C for 12 months.
Gene ID URL
2999
Predicted Cross Reactivity
Human, Mouse, Rat, Dog, Cow, Pig, Horse
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC042853-100 1x 100 µL
CD54 / ICAM-1 (15.2), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC470031-100 1x 100 µL
Mucin 5AC (MUC5AC) (45M1), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680676-100 1x 100 µL
MUC18 / Mucin 18 / CD146 (OJ79c), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details